Rohan Shirwaiker

Associate Professor

Rohan Shirwaiker is an Associate Professor in ISE and an Associate faculty member of the UNC-NCSU Joint Department of Biomedical Engineering. He is also the Associate Director of the Functional Tissue Engineering Program at the Comparative Medicine Institute (CMI).

Shirwaiker’s 3D Tissue Manufacturing research group focuses on advancing the science and technology for scalable manufacturing of engineered tissues. They study the fundamental relationships between 3D biofabrication processes, biomaterials, and critical-to-quality attributes of engineered tissues, and develop new tissue manufacturing strategies and platforms. Shirwaiker’s research is highly multidisciplinary and collaborative and has been supported by over $2.5 million in research grants from the National Science Foundation (NSF), Orthopaedic Research and Education Foundation (OREF), and Advanced Regenerative Manufacturing Institute (ARMI), and other funding agencies. He has co-authored over 100 journal articles, conference proceedings and book chapters, and has 3 patents on biomedical devices and processing technologies. He has been recognized by several awards including the NSF CAREER Award, SME Outstanding Young Manufacturing Engineer Award, SME Distinguished Faculty Advisor Award, IISE Manufacturing & Design Outstanding Young Investigator Award, and C. A. Anderson Outstanding Faculty Award.

Shirwaiker teaches undergraduate and graduate courses related to design and manufacturing, including ISE 316 (Manufacturing Engineering I: Processes), ISE 498 (Senior Design Project), ISE 589 (Intro to Biomedical Design and Manufacturing), and ISE 714 (Product Manufacturing for Medical Device Industry). He is the faculty advisor of the SME student chapter at NC State. He serves on the advisory committees of IISE’s Manufacturing & Design division and SME’s North American Manufacturing Research Institution and is a Program Chair of the 2020 IISE Annual Conference.
 

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Publications

Cell-Laden Nanocellulose/Chitosan-Based Bioinks for 3D Bioprinting and Enhanced Osteogenic Cell Differentiation
Maturavongsadit, P., Narayanan, L. K., Chansoria, P., Shirwaiker, R., & Benhabbour, S. R. (2021), ACS APPLIED BIO MATERIALS, 4(3), 2342–2353. https://doi.org/10.1021/acsabm.0c01108
Steroid eluting biocompatible stent for subglottic stenosis
Manzi, B., Shirwaiker, R., Gungor, A., & Weinberger, P. (2021), EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY. https://doi.org/10.1007/s00405-020-06562-y
3D bioprinting of anisotropic engineered tissue constructs with ultrasonically induced cell patterning
Chansoria, P., & Shirwaiker, R. (2020), ADDITIVE MANUFACTURING, 32. https://doi.org/10.1016/j.addma.2020.101042
Effects of Autoclaving, EtOH, and UV Sterilization on the Chemical, Mechanical, Printability, and Biocompatibility Characteristics of Alginate
Chansoria, P., Narayanan, L. K., Wood, M., Alvarado, C., Lin, A., & Shirwaiker, R. A. (2020), ACS BIOMATERIALS SCIENCE & ENGINEERING, 6(9), 5191–5201. https://doi.org/10.1021/acsbiomaterials.0c00806
Experimental Characterization and Finite Element Modeling of the Effects of 3D Bioplotting Process Parameters on Structural and Tensile Properties of Polycaprolactone (PCL) Scaffolds
Narayanan, L. K., & Shirwaiker, R. (2020), Applied Sciences. https://doi.org/10.3390/app10155289
High-Throughput Manufacture of 3D Fiber Scaffolds for Regenerative Medicine
Shirwaiker, R. A., Fisher, M. B., Anderson, B., Schuchard, K. G., Warren, P. B., Maze, B., … Pourdeyhimi, B. (2020), TISSUE ENGINEERING PART C-METHODS, 26(7), 364–374. https://doi.org/10.1089/ten.tec.2020.0098
Process hybridization schemes for multiscale engineered tissue biofabrication
Chansoria, P., Schuchard, K., & Shirwaiker, R. A. (2020), WILEY INTERDISCIPLINARY REVIEWS-NANOMEDICINE AND NANOBIOTECHNOLOGY. https://doi.org/10.1002/wnan.1673
Ultrasound-assisted vat photopolymerization 3D printing of preferentially organized carbon fiber reinforced polymer composites
Asif, S., Chansoria, P., & Shirwaiker, R. (2020), JOURNAL OF MANUFACTURING PROCESSES, 56, 1340–1343. https://doi.org/10.1016/j.jmapro.2020.04.029
Characterizing the Process Physics of Ultrasound-Assisted Bioprinting
Chansoria, P., & Shirwaiker, R. (2019), SCIENTIFIC REPORTS, 9. https://doi.org/10.1038/s41598-019-50449-w
Investigation of multiphasic 3D-bioplotted scaffolds for site-specific chondrogenic and osteogenic differentiation of human adipose-derived stem cells for osteochondral tissue engineering applications
Mellor, L. F., Nordberg, R. C., Huebner, P., Mohiti-Asli, M., Taylor, M. A., Efird, W., … Loboa, E. G. (2019), JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS. https://doi.org/10.1002/jbm.b.34542

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Rohan Shirwaiker