Rohan Shirwaiker

James T. Ryan Professor and University Faculty Scholar

Rohan Shirwaiker is the James T. Ryan Professor in ISE and Associate Director of the Functional Tissue Engineering Program at the Comparative Medicine Institute (CMI). He is also an associate faculty of the Department of Mechanical and Aerospace Engineering and the Joint Department of Biomedical Engineering.

Shirwaiker’s 3D Tissue Manufacturing research group focuses on the design and scalable manufacturing of engineered tissue products for biomedical and food applications. They engineer new bio-fabrication processes (e.g., ultrasound-assisted bioprinting, 3D nonwovens), biomimetic tissue designs (e.g., for tissue-engineered, orthopedic products, cultivated meats), non-destructive quality monitoring techniques (e.g., dielectric spectroscopy, ultrasound spectroscopy), and multimodal bioreactor designs for scale up/out. Using computational modeling, experimental approaches, and data analytics methods synergistically, they investigate fundamental interrelationships between critical process parameters, biomaterials, and functional quality attributes of the bioproducts. Shirwaiker’s research is highly multidisciplinary and collaborative and has been supported by grants from the National Science Foundation (CMMI, CBET), National Institutes of Health (NIAMS, NIDCR), US Department of Defense (ARMI BiofabUSA), Orthopaedic Research and Education Foundation (OREF), Eshelman Institute for Innovation, the Good Food Institute and others including the industry. He has co-authored over 150 journal articles, conference proceedings and book chapters, and has 3 issued/pending patents. He has been recognized by several awards including the NSF CAREER Award, SME Outstanding Young Manufacturing Engineer Award, SME Distinguished Faculty Advisor Award, IISE Manufacturing & Design Outstanding Young Investigator Award, and C. A. Anderson Outstanding Faculty Award.

Shirwaiker teaches undergraduate and graduate courses related to design and manufacturing, such as ISE 316 (Manufacturing Engineering I: Processes), ISE 498 (Senior Design Project), ISE 589 (Special Topics in Bio/Medical Design and Manufacturing), and ISE 714 (Product Manufacturing for Medical Device Industry). He is actively involved in volunteer roles with various professional societies including IISE (Diversity, Equity, and Inclusion Committee), SME (NAMRI Scientific Committee), ASME (Bioprinters Hardware Standards Committee) and others.


Research Interests

Bio-fabrication Processes and Systems, Tissue Engineering and Regenerative Medicine, Alternative Proteins Manufacturing, Bio/Medical Product Development 


Ph.D.Doctorate on Philosophy in Industrial EngineeringPennsylvania State University2011
MSMaster of SciencePennsylvania State University2007
BSBachelor of ScienceUniversity of Mumbai2005

Honors and Awards


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Investigating dielectric spectroscopy and soft sensing for nondestructive quality assessment of engineered tissues
Shohan, S., Zeng, Y., Chen, X., Jin, R., & Shirwaiker, R. (2022), BIOSENSORS & BIOELECTRONICS, 216.
Multiphase CFD Modeling and Experimental Validation of Polymer and Attenuating Air Jet Interactions in Nonwoven Annular Melt Blowing
Schuchard, K. G., Pawar, A., Anderson, B., Pourdeyhimi, B., & Shirwaiker, R. A. (2022), INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH, 61(37), 13962–13971.
Multiscale Anisotropic Tissue Biofabrication via Bulk Acoustic Patterning of Cells and Functional Additives in Hybrid Bioinks
Chansoria, P., Asif, S., Gupta, N., Piedrahita, J., & Shirwaiker, R. A. (2022, January 27), ADVANCED HEALTHCARE MATERIALS, Vol. 1.
Biofabricated 3D in vitro model of fibrosis-induced abnormal hepatoblast/biliary progenitors' expansion of the developing liver
Brovold, M., Keller, D., Devarasetty, M., Dominijanni, A., Shirwaiker, R., & Soker, S. (2021, June 5), BIOENGINEERING & TRANSLATIONAL MEDICINE, Vol. 12.
Cell-Laden Nanocellulose/Chitosan-Based Bioinks for 3D Bioprinting and Enhanced Osteogenic Cell Differentiation
Maturavongsadit, P., Narayanan, L. K., Chansoria, P., Shirwaiker, R., & Benhabbour, S. R. (2021), ACS APPLIED BIO MATERIALS, 4(3), 2342–2353.
Characterizing the Effects of Synergistic Thermal and Photo-Cross-Linking during Biofabrication on the Structural and Functional Properties of Gelatin Methacryloyl (GeIMA) Hydrogels
Chansoria, P., Asif, S., Polkoff, K., Chung, J., Piedrahita, J. A., & Shirwaiker, R. A. (2021), ACS BIOMATERIALS SCIENCE & ENGINEERING, 7(11), 5175–5188.
Fabrication of drug-loaded ultrafine polymer fibers via solution blowing and their drug release kinetics
Schuchard, K., Joijode, A., Willard, V. P., Anderson, B., Grondin, P., Pourdeyhimi, B., & Shirwaiker, R. (2021), 49TH SME NORTH AMERICAN MANUFACTURING RESEARCH CONFERENCE (NAMRC 49, 2021), Vol. 53, pp. 128–135.
Non-destructive quality monitoring of 3D printed tissue scaffolds via dielectric impedance spectroscopy and supervised machine learning
Shohan, S., Harm, J., Hasan, M., Starly, B., & Shirwaiker, R. (2021), 49TH SME NORTH AMERICAN MANUFACTURING RESEARCH CONFERENCE (NAMRC 49, 2021), Vol. 53, pp. 636–643.
Process hybridization schemes for multiscale engineered tissue biofabrication
Chansoria, P., Schuchard, K., & Shirwaiker, R. A. (2021). [Review of , ]. WILEY INTERDISCIPLINARY REVIEWS-NANOMEDICINE AND NANOBIOTECHNOLOGY, 13(2).
Steroid eluting biocompatible stent for subglottic stenosis
Manzi, B., Shirwaiker, R., Gungor, A., & Weinberger, P. (2021), EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY, 278(4), 1153–1158.

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Rohan Shirwaiker